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Role of Magnesium in Vitamin D Activation and Function

Uwitonze AM, Razzaque MS (2018) Journal of the American Osteopathic Association 118 181-189. doi:10.7556/jaoa.2018.037 

Web URL: Read this and related abstracts here. Free full text of this article is available online

Abstract:

Nutrients usually act in a coordinated manner in the body. Intestinal absorption and subsequent metabolism of a particular nutrient, to a certain extent, is dependent on the availability of other nutrients.

Magnesium and vitamin D are 2 essential nutrients that are necessary for the physiologic functions of various organs. Magnesium assists in the activation of vitamin D, which helps regulate calcium and phosphate homeostasis to influence the growth and maintenance of bones. All of the enzymes that metabolize vitamin D seem to require magnesium, which acts as a cofactor in the enzymatic reactions in the liver and kidneys.

Deficiency in either of these nutrients is reported to be associated with various disorders, such as skeletal deformities, cardiovascular diseases, and metabolic syndrome.

It is therefore essential to ensure that the recommended amount of magnesium is consumed to obtain the optimal benefits of vitamin D.

FAB RESEARCH COMMENT:

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And for more information on the importance of Magnesium and Vitamin D fo brain as well as body health, see also the following lists of articles, which are regularly updated: