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Zinc in psychosis (Review)

Theleritis C, Demetriou M, Stefanou M I, Alevyzakis E, Makris M, Zoumpourlis V, Peppa M, Smyrnis N, Spandidos D A, Rizos E (2025) Mol Med Rep 32(1):201. doi: 10.3892/mmr.2025.13566

Web URL: Read this research on PubMed

Abstract:

Zinc (Zn) may be associated with schizophrenia (SCH), since its altered homeostasis can contribute to abnormal glutamatergic neurotransmission, inflammation, neurodegeneration and autoimmune abnormalities. It has been proposed that a number of patients with SCH could benefit from the use of Zn, either on its own or along with vitamins C, E and B6, and prenatal supplementation of Zn during the gestation period can mitigate the lipopolysaccharideâ€‘induced rat model of maternal immune activation. The aim of the present review was to summarize the various effects of Zn dyshomeostasis on patients with psychosis and to clarify in what ways they could benefit from Zn supplementation.

< The metabolic role of vitamin D in children’s neurodevelopment: a network study

Theodoratou E et al 2014 - Vitamin D and multiple health outcomes: umbrella review of systematic reviews and meta-analyses of observational studies and randomised trials >

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