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Vitamins and Minerals - Clinical trials

Taking prenatal supplements associated with 30% lower risk of autism
Mitchell M et al 2025 - Protective effect of micronutrients used to treat antenatal depression on rates of postnatal depression at six months: A secondary analysis of NUTRIMUM
Katta et al 2024 - Micronutrients absorbed via the oral mucosa reduce emotion dysregulation in 5-10-year-old children: A three-phased randomized wait-list-controlled trial
For women with antenatal depression, micronutrients might help them and their babies – new study
Bradley et al 2024 - Efficacy and safety of a mineral and vitamin treatment on symptoms of antenatal depression: 12-week fully blinded randomised placebo-controlled trial (NUTRIMUM)
Third major study finds that multivitamin supplements improve memory and slow cognitive aging in older adults
Vyas C et al 2024 - Effect of multivitamin-mineral supplementation versus placebo on cognitive function: results from the clinic subcohort of the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial and meta-analysis of 3 cognitive studies within COSMOS
Blampied M et al 2023 - Efficacy and safety of a vitamin-mineral intervention for symptoms of anxiety and depression in adults: A randomised placebo-controlled trial “NoMAD”
Lange et al 2023 - Nutrition in the Management of ADHD: A Review of Recent Research
Dietary Interventions for ADHD: Emerging Research and Considerations
Dietary supplementation shown to improve nutrition biomarkers in study of older men
Michels A et al 2023 - Multivitamin/Multimineral Supplementation Prevents or Reverses Decline in Vitamin Biomarkers and Cellular Energy Metabolism in Healthy Older Men: A Randomized, Double-Blind, Placebo-Controlled Study
Taking a daily multivitamin appears to boost brains of adults over 60, but more study is needed
Vitamins, minerals improve symptoms for children with ADHD
Johnstone J et al 2022 - Micronutrients for Attention-Deficit/Hyperactivity Disorder in Youths: A Placebo-Controlled Randomized Clinical Trial
How small changes to prison food drastically cut inmate violence
LipiDiDiet finds broadly sustainable effects of nutrient intervention in early Alzheimer's
Roberts S et al 2020 - Effects of food supplementation on cognitive function, cerebral blood flow, and nutritional status in young children at risk of undernutrition: randomized controlled trial
Crime and Nourishment - Special Podcast Series
Firth et al 2019 - The efficacy and safety of nutrient supplements in the treatment of mental disorders
Do Nutrient Supplements Have Any Effect on Mental Disorders? World's largest review of the evidence
World's largest evidence review: Nutritional supplements for mental health
Micronutrients affect gut bacteria associated with ADHD in small but promising study
‘Limited’ methods: Expert urges caution over study claiming 'supplements can't prevent depression'
Nutritional supplements cannot prevent depression, research shows
Bot et al 2019 - Effect of Multinutrient Supplementation and Food-Related Behavioral Activation Therapy on Prevention of Major Depressive Disorder Among Overweight or Obese Adults With Subsyndromal Depressive Symptoms
Micronutrients in Psychiatry: Sound Science or Just Hype?
Dai et al 2019 - Magnesium status and supplementation influence vitamin D status and metabolism
Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder
Adams et al 2018 - Comprehensive Nutritional and Dietary Intervention for Autism Spectrum Disorder - A Randomized, Controlled 12-Month Trial
Rucklidge et al 2018 - Vitamin-mineral treatment improves aggression and emotional regulation in children with ADHD: a fully blinded, randomized, placebo-controlled trial
Hoenders et al 2018 - Natural Medicines for Psychotic Disorders: A Systematic Review
Marx et al 2017 - Nutritional psychiatry: the present state of the evidence.
Research consortium LipiDiDiet finds a way to impact Alzheimer's disease before it's too late
Soininen et al 2017 - 24-month intervention with a specific multinutrient in people with prodromal Alzheimer's disease (LipiDiDiet)
Special diets, supplements for autism still a question mark
Sarris 2017 - Clinical use of nutraceuticals in the adjunctive treatment of depression in mood disorders.
23 Feb 2017 - Nutraingredients - EPA-dominant omega-3 and other nutraceuticals can boost effectiveness of anti-depressants
Micronutrients for ADHD Symptoms in Children
Pelsser et al 2017 - Diet and ADHD, Reviewing the Evidence: A Systematic Review of Meta-Analyses of Double-Blind Placebo-Controlled Trials Evaluating the Efficacy of Diet Interventions on the Behavior of Children with ADHD.
Raine et al 2016 - Nutritional supplementation to reduce child aggression: a randomized, stratified, single-blind, factorial trial.
Omega-3 (with vitamins + minerals) lowers childhood aggression in short term
Strike et al 2016 - Omega-3 and Multinutrient Supplement Benefits Cognition and Mobility in Older Women: A Pilot Randomized Controlled Trial
Onakpoya & Heneghan 2015 - Efficacy of the novel medical food, Souvenaid, Alzheimer's disease: A systematic review
Supplements may improve teenage behaviour in school: Oxford researchers
Supplements save public health money: Review
Elia et al 2015 - Systematic review of cost and cost effectiveness of nutritional supplements in community and care home settings
Zaalberg 2015 - Nutrition, Neurotoxicants and Aggressive Behaviour
Elia et al 2015 - Systematic review of cost and cost effectiveness of nutritional supplements in the hospital setting
Scientists seeing 'dramatic improvements' in depression pill tests
Multivitamin may have pregnancy benefits over folic acid and iron alone: RCT
West et al., 2014 - Effect of maternal multiple micronutrient vs iron-folic acid supplementation on infant mortality and adverse birth outcomes in rural Bangladesh: the JiVitA-3 randomized trial.
Rucklidge et al, 2014 - Broad-Spectrum Micronutrient Treatment for Attention-Deficit/Hyperactivity Disorder
Gesch 2014 - Adolescence: Does good nutrition = good behaviour?
BBC News - Vitamins 'effective in treating ADHD symptoms'
Rucklidge et al 2014 - Vitamin-mineral treatment of attention-deficit hyperactivity disorder in adults: double-blind randomised placebo-controlled trial
Rucklidge & Kaplan 2013 - Broad-spectrum micronutrient formulas for the treatment of psychiatric symptoms: a systematic review.
Morse 2012 - Benefits of DHA, folic acid, vitamin D and iodine on foetal and infant brain development and function following maternal supplementation during pregnancy and lactation.
Harris et al 2012 - Effects of a multivitamin, mineral and herbal supplement on cognition and blood biomarkers in older men: a randomised controlled trial
Grima et al 2012 - The effects of multivitamins on cognitive performance: a systematic review and meta-analysis
Adams et al 2011 - Effect of a vitamin/mineral supplement on children and adults with autism
Harris et al 2011 - The effect of multivitamin supplementation on mood and stress in healthy older men
Hurt et al 2011 - Dietary and nutritional treatments for ADHD: current research support and recommendations for practitioners
Kamphuis et al 2011 - Effect of a medical food on BMI and activities of daily living in patients with Alzheimer's disease: secondary analyses from a RCT
Kamphuis et al 2011 - Efficacy of a medical food on cognition in Alzheimer's disease: results from secondary analyses of a RCT.
Brough et al 2010 - Effect of multiple-micronutrient supplementation on maternal nutrient status, infant birth weight and gestational age at birth in a low-income, multi-ethnic population
Zaalberg et al 2010 - Effects of nutritional supplements on aggression, rule-breaking, and psychopathology among young adult prisoners
Omega-3, vitamins, minerals may reduce aggressive behaviour
Scheltens et al 2010 - Efficacy of a medical food in mild Alzheimer's disease: A randomized, controlled trial
Haskell et al 2008 - Cognitive and mood effects in healthy children during 12 weeks' supplementation with multi-vitamin/minerals
Ames et al 2007 - Evidence-based decision making on micronutrients and chronic disease: long-term randomized controlled trials are not enough
Sinn & Bryan 2007 - Supplementation with PUFA and micronutrients on learning and behavior problems associated with child ADHD
The Guardian - Why it's time we faced fats
Gesch et al 2002 - Influence of supplementary vitamins, minerals and essential fatty acids on the antisocial behaviour of young adult prisoners. Randomised, placebo-controlled trial.
Nye & Brice 2002 - Combined vitamin B6-magnesium treatment in autism spectrum disorder.
Benton 2001 - Micro-nutrient supplementation and the intelligence of children
Peto 1991 - Vitamins and IQ.

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